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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		Allergy & Asthma Advocate: Fall 2006 The studies summarized below appeared in the August 2006 issue of the Journal of Allergy and Clinical Immunology (JACI), the peer-reviewed scientific journal of the American Academy of Allergy, Asthma & Immunology. Safe alternative to injection immunotherapy for seasonal allergy sufferers Grass allergen tablets are highly effective in grass pollen-induced rhinoconjunctivitis. This tablet represents a safe alternative to injection immunotherapy and is suitable for home use, according to a new study featured in the August 2006 issue of the Journal of Allergy and Clinical Immunology (JACI). Ronald Dahl, MD, and researchers studied the efficacy of a rapidly dissolving grass allergen tablet compared to a placebo in 634 patients with seasonal rhinoconjunctivitis. Subjects commenced treatment at least 16 weeks before the grass pollen season, and treatment was continued throughout the entire season. Researchers found: The primary efficacy analysis showed a reduction of 30% in rhinoconjunctivitis symptom score and a reduction of 38% in rhinoconjunctivitis medication score compared with placebo. Side effects mainly comprised mild itching and swelling in the mouth that was in general well-tolerated and led to treatment withdrawal in less than 4% of participants. There were no serious local side effects and no severe systemic adverse events. These findings suggest that sublingual immunotherapy with grass allergen tablets is effective in grass pollen–induced rhinoconjunctivitis. The tablet is well tolerated with minor local side effects. The grass allergen tablet represents a safe alternative to injection immunotherapy suitable for home use. <back>
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