After a severe allergic reaction without a known cause, a trigger should be identified if at all possible. An allergist/immunologist is the most appropriate medical professional to perform this evaluation1, which may include skin testing, in-vitro tests, and challenges when indicated (including with exercise – see below). Major triggers for anaphylaxis are foods and food constituents, medications and biologicals, latex, and insect stings.2-6 Future avoidance of the identified triggers should prevent subsequent anaphylactic episodes.
Management of idiopathic anaphylaxis by an allergist/immunologist is associated with a reduction in hospitalizations and emergency department visits.7
Diagnostic
Indirect outcome (trigger avoidance)
Direct outcome (idiopathic anaphylaxis)
Food allergy is the most common cause of anaphylaxis outside of the hospital setting.2, 3, 5 Allergist/immunologists employ diagnostic modalities to confirm the trigger, and use their specific training1 and clinical experience to educate patients regarding avoidance and immediate management to prevent potentially deadly outcomes.8
Diagnostic
Indirect outcome (food avoidance, early interventions)
After an anaphylaxic reaction that appears to have a significant relationship to exercise, it is crucial to be certain whether exercise is the cause and to determine whether or not a food might be involved.9-12
Diagnostic
Indirect Outcome
(avoidance)