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TOPICS
Overview
Allergic bronchopulmonary aspergilllosis (ABPA)
Anaphylaxis - Updated
Asthma
Asthma Diagnosis
Environmental diagnosis
and management
Asthma Treatment:
Immunotherapy
Asthma Treatment:
Preventing Morbidity
- Updated
Asthma Treatment:
Preventing Mortality

- Updated
Asthma Treatment:
Adherence
Occupational Asthma
Conjunctivitis
Cough
Dermatitis
Atopic - Updated
Contact
Drug Allergy - Updated
Food Allergy - Updated
Hypersensitivity Pneumonitis
Insect Hypersensitivity
Occupational Diseases
Primary Immune Deficiency - Updated
Rhinitis/Rhinosinusitis
Rhinitis - Updated
Sinusitis
Urticaria/Angioedema - Updated
How the Allergist/Immunologist Can Help:
Consultation and Referral Guidelines Citing the Evidence

Disease Group: Primary Immune Deficiency
  1. Any of the following warning signs:

    • Eight or more new infections within one year;
    • Two or more serious sinus infections within one year;
    • Two or more months on antibiotic with little or no effect;
    • Two or more pneumonias within 1 year;
    • Failure of an infant to gain weight or grow normally;
    • Recurrent deep skin or organ abscesses;
    • Persistent thrush in mouth or elsewhere on skin after age 1 year;
    • Need for intravenous antibiotics to clear infections;
    • Two or more deep seated infections;
    • A family history of immune deficiency.
    [Rationale]





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Frequent infection, unusual infections or unusual complications of usual infections are the most frequent presentation of immune deficiency1-7. Advanced diagnostic strategies are necessary to ensure appropriate diagnosis and treatment.1,6-9 Allergist/immunologists are trained to diagnose and treat primary immunodeficiency10. Immunologic therapy improves immunity11,12, reduces infections13-15, improves organ function16, prevents complications1, improves quality of life17, and may be curative18,19 in patients with primary immune deficiencies.
Diagnostic

Indirect outcome (immunologic therapy)